OpenSEM Forums

Adding covariates to sex-lim ACE model
Hi!
I'm new to twin data analysis and would like to get help on how to adjust for covariates in sex-lim ACE model. I tried to modify the script twinHet5AceCon.R by adding Age(continuous variable) and Region(binary variable)as covariates in the mean structure of the genetic model but I keep getting an error: Unknown reference 'meanGf' detected in the entity 'expMeanGf' in model 'MZf'.
I guess I may did something wrong somewhere near "expMeanGfmCo <- mxAlgebra( expression= meanGfm +Betaall %*% meanGfmCo , name="expMeanGfm" ) ".
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Importance of a path v/s factor
Hello!
I have a very general question that I would like to seek some help with. I know that the direct\indirect impacts for each variable in the model can be computed using a multiplication rule. However, this gives us the importance of the variable and not the path. How can I understand the importance of the path, should I simply add the co-efficients?
I would really appreciate a quick revert!
Thanks,
Vaibhav
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Model with latent variables
Hello!
I have a very general question regarding Covariance based SEMs. I have a full SEM model (with latent variables) and my client is wondering how a change in one attribute for one of the factors could affect the end dependent variable. Are standard SEM methodologies capable of answering this question? If so, how should I approach it?
A quick revert will be really helpful! Thanks!
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Unstandardized ML factor scores
I'd like to obtain unstandardized factor scores for a single factor CFA, with the factor scores on the same metric (approximately the same mean, SD, range, distribution) as the indicators. There is missingness in the data, so ML factor scores are preferred. How can I do this in OpenMX? I read Appendix A from Estabrook and Neale's (2013) paper on estimating ML factor scores in OpenMx:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773873/
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Need help
Hello Everyone, Please HELP
I am trying to test CFA with AMOS and I have some error messages that I couldn't understand.
I parceled the items in some scales but I recieve messages such as (Probability level cannot be computed)
OR
The model is probably unidentified. In order to achieve identifiability, it will probably be necessary to impose 1 additional constraint.
Anyone has any idea why the models didn't run? if you need more info please let me know
Thank you so much
Tamara
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Confidence intervals for shared environmental correlation are (-1.00, 1.00)
In a ACE bivariate Cholesky, any ideas why confidence intervals for a shared environmental correlation would be returned as (-1.00, 1.00)? My syntax is included below. The model converged without any errors.
bivACEModel <- mxModel("bivACE",
mxModel("ACE",
# Matrices a, c, and e to store a, c, and e path coefficients
mxMatrix( type="Lower", nrow=nv, ncol=nv, free=TRUE, values=.8, labels=c("a11","a21","a22"), name="a" ),
mxMatrix( type="Lower", nrow=nv, ncol=nv, free=TRUE, values=.8, labels=c("c11","c21","c22"),name="c" ),

3 level Longitudinal MLM - SEM
I have data with Counties nested within States over Time. I have been told that OpenMX is unable to run a three level MLM SEM and I need to use M+.
Can someone either confirm this for me or point me in the direction of some example code in OpenMX?
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Posterior predictive distribution and SEM
In short my question is: Are posterior predictive distributions used in the SEM world? If yes, under which name und for what purpose?
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Bivariate Cholesky Assumptions and CTCT Correlations
First time poster here. I'm learning generally about SEM and openMX at the same time and I want to run an ACE bivariate Cholesky decomposition with a sample of twins. I'm using the script below to test assumptions of the model and then run the Cholesky. (This is very similar to existing scripts that are posted, I just added some elements to get confidence intervals for the genetic/shared environmental correlation, and also the phenotypic correlation.)

eQTL analysis & IBD
Dear all,
I would like to perform an eQTLs analysis with OpenMx using a IBD matrix inferred by using genotype data. The model I would like to evaluate is the ACQE one. Does someone have some scripts I can use/adapt or some hints about how to deal with this?
Thank you very much!
Alessia
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