Behavioral Genetics Models

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No user picture. Qiuzhi Xie Joined: 12/27/2018

Question about Confidence Interval for Standardized path coefficients (multivariate model)

Hi everyone, I am new here and learning OpenMX. I have a problem of getting confidence interval for standardized path coefficients. Could anyone please provide me the OpenMx language about this? I also provide my scripts below and hope someone can let me know what the problem is (the script about 'ciACE <- mxCI("VC[1:5, 16:30]")' ) or how to read the output about standardized CI.

# Load Data
nl <- read.csv(file="C:/R/TwinPairACE.csv", header=TRUE, sep=",")

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Picture of user. chancey Joined: 09/09/2017
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No user picture. Mirch Joined: 10/26/2018

Adding covariates to Cholesky script

Hi there, I am a new PhD student working on a project with twins for the first time. I've been provided with some older scripts from past students and some example code from a twin analysis workshop in Queensland that I haven't been able to attend yet (which I believe was run by Sarah Medland).

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No user picture. George Richardson Joined: 10/18/2018

Sex Limitation Model Question

Hi,
I attended the Boulder workshop a couple years ago and am now trying my hand at sex limitation modeling. Currently, I am working on a same-sex twin pair sex limitation model for liability to alcohol use disorder. I've found measurement invariance and A and C are invariant. C was non-sig. and is constrained to zero. The AUD factor intercept is invariant. Can I interpret the sex difference in the AUD means in terms of greater genetic risk for AUD in the males?

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No user picture. Aurina Joined: 01/05/2016

ACE including non-twin siblings

Dear all,

I'm trying to adapt ACE heritability model to include both twins and their non-twin siblings. The data used for the analysis are imaging-derived phenotypes from the human connectome project (HCP) which includes both MZ and DZ twin pairs as well as their non-twin siblings for a subset of twins. Would be really helpful if anyone could answer a few questions.

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No user picture. sealx017 Joined: 08/17/2018

Multivariate cholesky model

Hi,

I have a dataset of twins on 4 time-points. I can fit the Multivariate cholesky decompositon model with ACE components. It considers unstrcutured covariance matrices for A, C and E component. I was wondering if its possible to restrict it to a special structure? Like, say compound symmetric or AR1.

Thanks

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No user picture. massimiliano.orri Joined: 06/11/2018

Latent Growth Model and distal outcome

Hi,
I would like to fit the twin model in the enclosed figure, but I am not sure if this is feasible.
Can someone help me understanding if the model is identified?
In case, are there any exemples of R code for this model?
Thanks a lot
M