Hello,
I have completed a standard ACE model of a phenotype with no errors. I now want to permute the zygosity labels of the twins and perform 10,000 permutations of the ACE model. I will then use this distribution of permitted A estimates to estimate the significance of my observed A.
When I run the analysis with the observed data I receive no warnings. However, when I run the permutations I usually receive about 20 of the warnings shown at the bottom of this message. Based upon the info in this forum https://openmx.ssri.psu.edu/thread/754 it seems like this error is most likely from when the permutations are operating on the extremes of the model and are safe to ignore.
However, I am not sure how to confirm this is the case with so many models to work with.
Thanks!
Brittany
In model 'ACE' Optimizer returned a non-zero status code 6. The model does not satisfy the first-order optimality conditions to the required accuracy, and no improved point for the merit function could be found during the final linesearch (Mx status RED)