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twoACE_Cholesky.R [6] | 8.57 KB |
I am estimating a Cholesky decomposition ACE model and deriving the rA, rC, and rE estimates. The confidence intervals are not estimating for many of these parameters. There appear to be varying diagnoses when I use verbose=T (i.e., active box constraint, alpha level not reached infeasible non-linear constraint). I have tried choosing a different optimizer, re-scaling the phenotypes, using mxTryHard, and changing start values. The univariate variance components as well as their correlations are significant. I would appreciate any guidance regarding how to obtain these confidence intervals.
Please note we will also look at the correlated ACEs with direct variance but this is in response to a reviewer request for the Cholesky.