# Moderated bivariate ACE

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Hasan
Joined: 03/07/2023

I'm trying to fit a moderated bivariate ACE model such as the one seen in the attached picture.

Is there a way to do this in umx? As far as I can tell, neither umxGxE nor umxGxEbiv do exactly this. Can they be expanded to fit this particular model?

I've tried to get my head around using OpenMx rather than umx, but with little success :-) But I found this script from the Boulder materials - https://vipbg.vcu.edu/media/course/HGEN619_2015/twin2ModBivAceCon.R, am I correct that this fits the model I'm trying to fit?

Thanks!

## umxGxEbiv

In practice, the models are often quite hard to estimate.

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## umxGxEbiv

In practice, the models are often quite hard to estimate.

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In reply to umxGxEbiv by tbates

## Thanks! Well, there's two

- umxGxEbiv includes *one* variable plus a moderator, right? Trying to add two selDVs using c() gives the error "selDVs list must be 1 variable...". So I don't see how I can use it to investigate how a moderator impacts the relationship between two other variables.

- The moderator I have in mind is SES, so it doesn't differ between twins. Although I'm early in my research so I could go for a slightly different hypothesis.

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In reply to Thanks! Well, there's two by Hasan

## (Is it better to just run

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