Behavioral Genetics Models
JuanJMV
Joined: 07/20/2016
Sex-Limitation model in two different cohorts
I am trying to fit a sex-limitation model (5 groups) but in two different cohorts (1944-1980) and (1981-2000). So, I have 10 groups (MZM, MZF, DZM, DZF and DZO x 2 cohorts).
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bjoyner
Joined: 01/28/2022
Bivariate Cholesky Decomposition Model - Negative Unique Environment Estimate
I am attempting to examine the covariance between two variables (callous, vict3_cfa) using a bivariate cholesky decomposition model. However, when I run the models, the unique environment estimate for the best fitting model comes out as negative.
valentinav
Joined: 06/15/2020
multilevel twin analysis
Participants of my study completed a 40 trials decision-making task.
The issue is that I do not have access to many twins, so I would like to increase the power of my study considering trial level data, instead of the mean of all trials of each subject.
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valentinav
Joined: 06/15/2020
correcting raw score for age and gender
I received suggestions to correct the the raw score for age and sex main effects, and for the age x sex interaction. However, I am not familiar with this procedure, does someone knows more about it?
So far, what I had done was to insert age a covariate in my analysis.
Thanks!
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EmilieRH
Joined: 09/24/2020
Full bivariate moderation model
I am trying to investigate how school performance modifies the genetic and environmental influences on intelligence running a full bivariate moderation model (a la the extended GxE model in Purcell 2002). However, my OpenMx results differ a lot from what my collaborator has obtained using the old Mx software, so I really hope that one of you can help me figure out what I have done wrong in the attached script.
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JuanJMV
Joined: 07/20/2016
Correlations from ADE and AE, huge differences
I am writing this post since I am fitting an ADE bivariate model, but I get really different correlations from the ADE and the AE model.
Here you can see the correlations for both models:
mirusem
Joined: 11/19/2018
Paul Jeffries
Joined: 07/02/2021
Non-family GXE with G-->E
I used the R package gwsem to conduct a GxE analysis without the effect of G on E. However, I can not use it for the current analysis since the package does not permit a term to be a covariate and a dependent variable.
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Mirch
Joined: 10/26/2018
Negative ACE estimates in Univariate Model
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diana
Joined: 04/17/2019
Model-averaged point estimates
I am trying to calculate the heritability for some fat-related traits. I have fitted the ACE model and some submodels (CE and AE) and then learned that it was recommended to use mxModelAverage() to gain the model-averaged point estimates.
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